I am very conservative but it is hard to estimate peak sales potential of 2-73, if price 2-73 at 10K/year cost for PDD and ALD, 2-73 is going to have the highest revenue/year without a doubt, Humira has the title so far with $20B sales in 2020. I know street normally give 1 time peak sales potential MC after PII efficacy data strongly point to PIII and approval success.