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FitzyP33

10/14/21 1:00 PM

#332917 RE: ignatiusrielly35 #332915

My point is only that nothing is a foregone conclusion. I put that statement at the same level as when someone was asking who's a AVXL millionaire on this MB a few months ago. The moment that was asked the stock dropped 50%. Same with "foregone conclusion." Don't go there. Say so with the data we've seen so far it looks promising. Stuff like that. Just not foregone conclusion.

Even Rett great results this year won't move the stock price much unless it comes with BTD, accelerated approval by the FDA, etc. Otherwise, yes it's good, but still a yawn until AVXL can actually sell something.
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Steady_T

10/14/21 2:58 PM

#332925 RE: ignatiusrielly35 #332915

Children should respond better than adults. At the same time children are vulnerable to developmental issues that adults are not so there is a greater opportunity for negative things to show up in the trial.

I suspect that the recent increase in trial size to allow age grouping analysis of the results is an effort to quantify those possibilities.

If the pediatric trial does not uncover any age related issues then 2-73 is golden.