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Steady_T

08/14/21 1:57 PM

#325933 RE: georgejjl #325932

Exactly what I was referring to.

We didn't see that in the AD data. The Rett data may show such an effect at the higher doses.
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frrol

08/14/21 5:09 PM

#325961 RE: georgejjl #325932

Not an asymptote, a "maxima". Asymptotes arise from mathematical functions that approach (never meeting) a limit as some "x" goes to an infinity.

This is not a mathematical function, it's a physiological process: a charted dose (a finite "x") response would have a maxima(s).