Replies to post #325339 on Anavex Life Sciences Corp (AVXL)

[Gator328]

I wouldn't discount a complementary role for a partner -- I mentioned this with a possible AVXL / SAVA merger earlier, but CRTX may make more sense. It'll take a while though because while both drugs are safe on their own, a trial would be needed to study the safety and efficacy when taken together.

My concern is that the FDA won't want to approve more than 2 Alzheimer's drugs within a year. Aducanumab is a placeholder until something better comes along, so it's a race to see who gets to replace it. Anavex is probably on a slower track for Alzheimer's, which is why I like that Dr. Missling is also focusing on Rett and Parkinson's. If/when it gets approved for Alzheimer's, it'll boil down to the data and which drug is more effective between AVXL, CRTX and SAVA

[nidan7500]

infit

I don't gather from the Data that CRTX can reverse or improve symptoms that have already formed. I also don't see the infection being the sole cause, more or less just another contributing factor. If that turns out to be correct, couldn't these 2 drugs complement each other?

I think this is an extremely important key observation. Have not seen any CRTX claim on resetting or restoring cognitive suite of functions as claimed w/A2-73 % of Homeostasis MOA. Another point might be that wouldn't a nice new life long set of dental implants be a better (cheaper-faster-more certain)solution?

Not sure this proposed set of CRTX treatments has been critically evaluated yet.