How are the days and time of recovering computed for all the WW untreated patients and families considered? When we have n=400 patients in trials recovering or stable while we have n=2,000,000+ awaiting treatment and possible stabilization or recovery, what statistical weight is given for their potentially positive treatment?
Considering that no AD patient has ever been successfully treated, results after 30+ years of research show AD a death sentence. I think we all get the risk of being wrong while a treatment produces little to no positive results. (so what...in some context)
This is also all about the use of time and the fact that everyone only has a finite amount of it. There are many positive and negative observations made during trials, anecdotes yes but valid when done correctly. Some trials are stopped due to futility. What about a little risk management logic based on comparisons and anecdotes which are somehow qualified and precisely quantified to advise everyone who needs to know.
If I was in a trial w/AD and no QOL at all, I would certainly ask to be given a positive option, even a remote one. Nothing to loose.
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