Replies to post #389173 on NorthWest Biotherapeutics Inc (NWBO)

[Extremist223]

WHO has removed IDHmt aka IDH mutant from the GBM classification.

WHO is keeping IDH wild-type within the definition of GBM. All GBM is now comprised of 100% wild-type.

This is very good for NWBO. Confusion is not.

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Quote:
Glioblastoma is now defined as a diffuse astrocytic glioma with no mutations in IDH genes nor histone H3 genes and is characterized by microvascular proliferation, necrosis and/or specific molecular features, including TERT promoter mutation, EGFR gene amplification and/or a +7/–10 cytogenetic signature. — https://www.nature.com/articles/s41571-020-00447-z
December 8, 2020


Could you clarify this?