Replies to post #315722 on Anavex Life Sciences Corp (AVXL)

[infitvest]

Maybe Biostock will give us a little nugget to research :)

I find myself in the same boat. Even as we speak I have extra funds laying around. 1 AVXL core and 1 AVXL trading turned into 2 Anavex cores lol... I'd buy more and tell myself I'll sell them on the next big pop... but who am I kidding, I'm in this till the end and revenue is being generated!

I've taken a look at a few mentioned on here, I just don't see anything with a shred of Anavex's potential. Debated on doing more research on annovis and cortexyme. Annovis being something that might work with 2-73 and the later company because its either right and everyone is wrong haha...or its gonna tank on me with a readout in November :).

[Bud Powell]

It seems to me asset allocation and risk tolerance certainly plays a huge part. I'm woefully - by any measure - overweighted in AVXL, but I'm swinging for the fences with a small bat. Not sure I'd be able to handle my overweight % if I had gazillions or even millions. Benny was the only person I saw that posted here that had more % wise; I think he posted he was betting the whole farm on it, so, I'm assuming close to 100%. As the price goes higher I'm torn between (1) rebalancing (2) FOMO. btw, none of my business really, but I wonder what sort of allocation TGD has; a reasonable 3-5% or more than 50%. As some have posted here, Fidelity considers 5% to be a concentrated (I think was the term) position. But yeah, besides some cash for emergencies, some swing trading, seizing other opportunities, where is a better place to invest than Anavex? Real estate? I heard on the news (Tucker Carlson) that Blackrock is buying up houses everywhere paying more than listed price thus raising prices.

[Investor2014]

Maybe the $AVXL risk has gone down, but the impact of an adverse risk event has gone up.

Certainly in the relative sense one can now lose say more than 10 times the value of the original investment if that was at $2 per share. I think that would feel unpleasant.

In an absolute sense by not rebalancing, one could likely not be worse off than 5 or 10 years ago whenever first invested in $AVXL. If on the side one has also traded $AVXL that could well exceed the time value of a complete reset in share price.

Now rebalancing by selling say 50% of $AVXL perhaps on 10 times gain would lock in a great return.

The question is then whether the fear of loosing out on another 1000% gain is greater and importantly more impactful than potentially loosing a large proportion of the paper gains shown on the current broker statement.

In a biotech portfolio the risk that any one stock takes a near 100% nosedive is far greater than the possibility than one see thousands of percent gains in a ‘we got this’ manner.

Alas this is the human investor’s condition and we takes our picks.

[jimmy_mcyoloswag]

My thoughts too. If the Rett data is excellent, I'll hold and wait for dividends, maybe sell to recover up to my initial investment if need be. If not excellent, rebalancing. If ambiguous to bad -> sell all but foot in the door for less likely dementia upside.

[baltimorebullet]

I think it depends how well you know yourself.

About a year ago my AVXL position was about 10x my normal position size.
I was 61 years old, not wealthy, and this seemed awful risky.
I was uncomfortable and sold half.

I immediately knew it was the right thing to do for me.
Do I now regret this?
No, that would be foolish and playing hindsight games.
For the last year I've enjoyed AVXL's progress stress free.


I would recommend most sell some and bank the money, keep some and enjoy the ride.
If you know you'll beat yourself up if you sell some and the share price continues to rise and you'll beat yourself up if you don't sell some and it tanks, you should get to know yourself better and then act accordingly.

In the interest of full disclosure I did increase my position by 20% @$12 a share a few months ago.

https://mebfaber.com/2013/07/26/just-go-halfsies/

https://seekingalpha.com/article/131980-the-wisdom-of-half-positions