I often consider the end of a month to be the third Friday. June options are not available yet and July is too risky. I expect an announcement of full enrollment for the 2b/3 in May which could cause a wobble in the SP but not a major move (enrollment is expected and results not out till Q2 or Q3 2022). There are a couple wild card PRs that could come out anytime. More details of the US Rett study (I suspect they have the finer detail data but may need to process further with Ariana) has potential to move the stock price as absolute value data could be compared to trofinetide. If the comparison is favorable, release could be anytime but if similar to trofinetide numbers, I would not expect the release of the additional data until after or concurrent with the AU Rett topline results. I baked those possibilities into the decision to sell May $12 puts and $18 CC. Premiums are rich for OTM. A bunch of 12.5 short puts sold a month ago will expire April 16 --- chance of bad news in next week is small.