Why oh why did they put recurrence - you know - RECURRENCE - in the thingie thing. And the SAP too
(I'll bet their all partial resections.)
And then there is this -
SA - 20th
methylated MGMT gene, which is present in 40% GBM patients
perspective
Another very interesting thing to note: The interim analyses were blinded. That means, while they saw that patients in the trial survived for a median of 23.1 months at that time (34.7 for patients with a methylated MGMT gene, which is present in 40% GBM patients), which is a vast improvement over historical rates (of 19.6 months for TMZ+Optune and 15.2 months for TMZ alone, see here), they could not know which patients survived longer, SoC+placebo patients or SoC+DCVax-L patients.
If we reached 40% your talking 132 patients If we reached ~30% your talking 100 patients
Who knows - VAX + TMZ in methylated MGMT might be an eye opener