Replies to post #335011 on NorthWest Biotherapeutics Inc (NWBO)

[VuBru]

Jammy -
Here is the impact of gross resection vs. not from the JTM article:

"For patients with gross total surgical resection (n=209), mOS was 25.4 months from surgery (95% CI 21.8–28.2), with 2 and 3-year survival rates of 51.2%, and 29.9%, respectively. For patients with only partial surgical resection (n=122), mOS from surgery was 21.1 months (95% CI 19.1–23.1), with 2 and 3-year survival rates of 37.7%, and 18.0%, respectively (Table 2).

In patients with both MGMT methylation and gross total resection (n=83), the mOS was 36.5 months (95% CI 31.5–46.5)—1.8 months longer than the mOS of patients with MGMT methylation and only partial resection (n=48). In patients with unmethylated MGMT, there was no statistically significant survival advantage with gross total resection compared to only partial resection."