The virosome formulations will incorporate and evaluate two different SARS-CoV-2 antigens, one full length stabilized S protein, for which Mymetics is collaborating with the group of Dr. Rogier Sanders at the Amsterdam Medical Center of the University of Amsterdam, the Netherlands, and the second is a receptor binding domain recombinant protein of SARS-CoV-2.
Do you see what the man (Dr Kempers) is trying to tell you b/c it isn't the first time we round about heard that
If the gal @ Baylor see's what she wants then we could be in a good place here
Release of Immunomodulatory Ebola Virus Glycoprotein-Containing Microvesicles Is Suppressed by Tetherin in a Species-Specific Manner
Virosome 133 times
Highlights
The Ebola virus glycoprotein (GP) drives the release of GP-containing virosomes
Tetherin restricts GP-virosome release through transmembrane domain interactions
GP-virosome release is most efficient for GPs of highly pathogenic Ebola viruses
Immunomodulatory GP-virosomes serve as decoys for EBOV-neutralizing antibodies
2 Institute of Virology, Helmholtz Zentrum Munchen, German Research Center for Environmental Health, 85764 Neuherberg, Germany
ACKNOWLEDGMENTS
We would like to thank Gerhard Jahn and Thomas Iftner for constant supportand encouragement and Ulrike Protzer for providing continued access to the research facilities at the Helmholtz Center Munich. Furthermore, we thank Daniel Sauter, Paul Bieniasz, and Thomas Gramberg for providing reagents and Thomas Hoenen for the trVLP system. This work was funded by grants to S.P. and M. Schindler from Deutsche Forschungsgemeinschaft (SCHI1073/4-1 and PO 716/8-1). Furthermore, M. Schindler received institutional support from the Helmholtz Center Munich, German Research Center for Environmental Health, and the University Hospital Tuebingen.
The Helmholtz Association pursues the long-term research goals of the state and society, including basic research, in scientific autonomy. To do this, the Helmholtz Association conducts top-level research to identify and explore the major challenges facing society, science and the economy. Its work is divided into six research fields. The Helmholtz Association brings together 19 scientific-technical and biological-medical research centers. With more than 42,000 employees and an annual budget of over € 5 billion, the Helmholtz Association is Germany's largest scientific organisation. The Association's work follows in the tradition of its namesake, the natural scientist Hermann von Helmholtz (1821-1894).