Replies to post #20786 on Mymetics Corp (MYMX)

[Work Harder]

Pevion's virus-like particle (VLP) vaccine technology, called virosomes, and its architecture is specifically designed to produce safe and efficient vaccine subunits. Virosome-based vaccination is effective in reliable regulatory and safety records as well as the feasibility of upgrading production and has been approved in more than 40 countries, including infants and older people. The prospect of drug delivery and targeting using virosomes is a vital area of research and development. This review pinpoints the various aspect of virosome and will be a milestone for the researchers in the field of drug delivery.

That from 2nd link

Volume 11 Issue 4

DOI: https://doi.org/10.26452/ijrps.v11i4

Published: Oct 7, 2020

Original Articles

https://pharmascope.org/ijrps/issue/view/48

ArticleHistory:Receivedon:03Jun2020Revisedon:05Jul2020Acceptedon:06Jul2020

https://pharmascope.org/ijrps/article/view/3230/7179

CONCLUSION

The virosomal drug delivery system is an intelli-gentapproachfortargeteddeliveryofdrugsandseveralotherbiologicallyactivemolecules,partic-ularly nucleic acids or genes. The main motivebehind the development of virosomal techniqueis to overcome the limitation of inadequate drugdeliverytowardstargetedcells,tissuesandorgansof the body. Virosomes are biodegradable, non-5818©InternationalJournalofResearchinPharmaceuticalSciences
SreejaCNairetal.,Int.J.Res.Pharm.Sci.,2020,11(4),5809-5820poisonous, biocompatible and non-auto immuno-genicunilamellarphospholipidbilayervesiclesthatcompriseproteinsderivedfromviruses. Antigenscan be delivered to the host body using variousroutesofadministrationlikeintradermal,intramus-cular and intranasal route, depending upon theaim of immunisation. Virosomes are consideredasaneffectiveprophylacticandtherapeuticagentdue to their added advantage of tissue targetingimmuneactivation&potentiationoverothertar-geteddrugdeliverysystems. Hence, theycanbewidelyusedinthe?ieldofcancertherapyasacar-rierforimmunomodulatingmoleculesaswellasfortargeteddrugs.ApplicationofVirosomeinthe?ieldoftargeteddrugdeliverysystemwillbringanewopportunity&alsoopenanewerainthemodernpharmaceuticalsector&humanlifetoo.

[Work Harder]

6. Scale-up problems can be compounded by choosing the right preparation and decontami-nation process by autoclaving or membrane fil-tration together witha septic & validated pyro-gen removal Lal test.

Millipore

Filter Integrity
Test Methods

https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwiUv_SW6cjsAhWKK80KHVN6D5wQFjACegQIBBAC&url=https%3A%2F%2Fwww.emdmillipore.com%2FWeb-PR-Site%2Fen_CA%2F-%2FUSD%2FShowDocument-File%3FProductSKU%3DMM_NF-C2054%26DocumentId%3D201306.9919.ProNet%26DocumentUID%3D5320596%26DocumentType%3DTI%26Language%3DEN%26Country%3DNF%26Origin%3DPDP&usg=AOvVaw2mi6J6TMH5O-69Vd-PRtdm

Millipore AG technology de separation

Chemin de Maillefer 43, 1052 Mont-sur-Lausanne, Switzerland

C/o Merck (schweiz) Ag Chamerstrasse 174 Zug, 6300 Switzerland

https://translate.google.com/translate?hl=en&sl=de&u=https://ydo.ch/companies/309720/millipore-ag-technologie-de-sparation/&prev=search&pto=aue

MilliporeSigma today celebrated the topping-out ceremony for its new membrane production plant in Darmstadt, Germany. With the new facility, the company plans to expand manufacturing of Millipore Express® membranes, which are critical components in Millipore Express® filters and help ensure the sterility of biological drug products. The project with a volume of more than $165 million is part of the $1.2 billion investment in its global headquarters until 2025 that MilliporeSigma’s parent company, Merck KGaA, Darmstadt, Germany, announced last year.

https://www.emdmillipore.com/US/en/about-us/news-media-room/press-releases/yoqb.qB.f2UAAAFEbSVRnx1I,nav

[Work Harder]

Virosome immunisation of mice provided full immunity against Ebola infection for vaccinated mice (Sunetal.,2010). The virosomes are, therefore, an essential instrument in the production and manufacture of vaccines. Further evaluation can also help to establish virosomes for coronavirus in future.

For example, anticancer drugs will be transmitted particularly to tumours by marking the virosomes with antibodies

GO BEARS

[Work Harder]

Overview on virosomes as a novel carrier for drug delivery

Review article

Dr. Shaikh Siraj N*, Shahid Raza, Mohd. Aslam Ansari, Dr. G.J. Khan, Siddiqi Hifzurrahman MD Athar Department of Pharmaceutics, Ali-Allana College of Pharmacy Akkalkuwa, Dist. Nandurbar, Maharashtra, India-425415

https://www.researchgate.net/publication/330437561_Overview_on_virosomes_as_a_novel_carrier_for_drug_delivery

Sreeja C Nair

m pharm
Project

https://www.researchgate.net/profile/Sreeja_C_Nair

Top co authors

Visakh Prabhakar

Novartis · Competitive Intelligence

M.Pharm

https://www.researchgate.net/profile/Visakh_Prabhakar