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Replies to #39181 on Biotech Values
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DewDiligence

12/14/06 1:04 PM

#39185 RE: Praveen #39181

>Speedel / NVS – The [Tekturna] dose tested in rats was 600mg while in humans it is 300mg.<

I assume you mean that the rat dose was 600mg on a weight-adjusted basis. Has NVS disclosed this?

If true, I consider this bearish for Tekturna. A 2x safety margin is pretty small in the logarithmic world of biology.