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DewDiligence

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Re: Praveen post# 39181

Thursday, 12/14/2006 1:04:19 PM

Thursday, December 14, 2006 1:04:19 PM

Post# of 257648
>Speedel / NVS – The [Tekturna] dose tested in rats was 600mg while in humans it is 300mg.<

I assume you mean that the rat dose was 600mg on a weight-adjusted basis. Has NVS disclosed this?

If true, I consider this bearish for Tekturna. A 2x safety margin is pretty small in the logarithmic world of biology.

“The efficient-market hypothesis may be
the foremost piece of B.S. ever promulgated
in any area of human knowledge!”

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