Replies to post #204022 on Anavex Life Sciences Corp (AVXL)

[TTTav66]

Thanks for sharing this kevli33. I've briefly reviewed the paper and there is a nice overview covering Sigma-1 receptor science in the section, The role of Calcium homeodynamics in cellular senescence, aging, and AD. This section concludes with:

For its large spectrum neuroprotective effect due to an extensive capacity to modulate intracellular calcium shuttling, S1R have been increasingly recognized as novel main candidate targets to prevent or delay AD-related pathophysiological processes.

https://www.sciencedirect.com/science/article/pii/S0301008218302107?via%3Dihub