Replies to post #197013 on Anavex Life Sciences Corp (AVXL)

[nidan7500]

Excellent stuff here Cbd...

An agnostic, hypothesis-free, unbiased systems theory approach seems better suited to explain the complex and heterogeneous origin and time course of the pathophysiological failure underlying different forms of AD4. For multifactorial dis- eases like AD, comprehensive holistic systems-level approaches are necessary; this is the case of the SB model, which aims at understanding the genotype–phenotype rela- tionships and the mechanisms at the level of genome/epi- genome, transcriptome, microRNome, proteome/peptidome, metabolome/lipidome, microbiome, lifestyle, and environ- mental factors participating in complex cellular net- works3,4,43. Correspondingly, SB is based on: (1) advanced molecular and high-throughput ‘omics’ methods disclosing and characterizing biomarkers associated with disease mechanisms, and (2) computational and integrative network biology tools for assimilating multimodal information to comprehensively understand the systems-level dysfunc- tion44.

Excellent stuff here. Very much looking forward to …"BIOMARKERS..The AD Musical", coming to a theater near you staring HH and the original AVXL-AUS staff". ..