George - Thanks for throwing light on the matter of sleep deprivation! I believe the sleep market will improve greatly when ANAVEX is approved, possibly before any other indication depending on trial results.
„By contrast, chronic sleep restriction but not acute sleep loss activates microglia, promotes their phagocytic activity, and does so in the absence of overt signs of neuroinflammation, suggesting that like many other stressors, extended sleep disruption may lead to a state of sustained microglia activation, perhaps increasing the brain's susceptibility to other forms of damage.“
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