Probiodrug's lead product candidate, PQ912, is a highly specific and potent inhibitor of Glutaminyl Cyclase (QC), the enzyme catalyzing the formation of synaptotoxic pGlu-Abeta. PQ912 has shown therapeutic effects in AD animal models.
My very cursory knowledge to the arcane chemistry of immunology prevents any useful assessment of the matter.
Nor can I speculate on any sort of Anavex synergy. Have no idea. Anavex being Anavex, couldn't rule it out.
Both of us know of the profound connection and interaction of the gut microbiome and the immune system. You will be watching this for us. Thanks.