So.... They have the same delivery approach of using Dendritic Cells like eTheRNA does. Funny, with all the preparation complexities they're doing with their material, eTheRNA simplified everything by using a messenger RNA (mRNA) to be delivered to the dendritic cells using our virosomes.
Directing the delivery
"Hubbell and his colleagues approached this problem as a delivery issue. To deliver the vaccine to its intended target, they developed a vaccine platform made up of a polymeric adjuvant—which contains multiple adjuvant molecules connected like pearls in a necklace—coupled with an antigen. This platform can easily drain into the secondary lymphoid tissues".
"To make sure it found its way to the intended site, they incorporated mannose, a type of sugar, into the polymeric adjuvant. Because viruses and bacteria tend to have a lot of sugar on their surfaces, the dendritic cells in the lymphoid tissues have several sugar receptors that help in the recognition of pathogens".
"So once the mannose-laden vaccine is injected into the body, it targets specific immune cells called dendritic cells, which in turn activate T cells. By specifically targeting dendritic cells, this new technology prevents systemic inflammation while efficiently activating an immune response".
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