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Re: Phosphene post# 12238

Monday, 02/04/2019 8:43:35 PM

Monday, February 04, 2019 8:43:35 PM

Post# of 27661
So.... They have the same delivery approach of using Dendritic Cells like eTheRNA does. Funny, with all the preparation complexities they're doing with their material, eTheRNA simplified everything by using a messenger RNA (mRNA) to be delivered to the dendritic cells using our virosomes.


Directing the delivery

"Hubbell and his colleagues approached this problem as a delivery issue. To deliver the vaccine to its intended target, they developed a vaccine platform made up of a polymeric adjuvant—which contains multiple adjuvant molecules connected like pearls in a necklace—coupled with an antigen. This platform can easily drain into the secondary lymphoid tissues".

"To make sure it found its way to the intended site, they incorporated mannose, a type of sugar, into the polymeric adjuvant. Because viruses and bacteria tend to have a lot of sugar on their surfaces, the dendritic cells in the lymphoid tissues have several sugar receptors that help in the recognition of pathogens".

"So once the mannose-laden vaccine is injected into the body, it targets specific immune cells called dendritic cells, which in turn activate T cells. By specifically targeting dendritic cells, this new technology prevents systemic inflammation while efficiently activating an immune response".

https://medicalxpress.com/news/2019-02-vaccine-malaria-effective.html
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