Replies to post #175866 on Anavex Life Sciences Corp (AVXL)

[OFP]

The "Activation of sigma-1 receptor chaperone in the treatment of neuropsychiatric diseases and its clinical implication" paper suggests, like the one I referred to earlier, that the positive effect of Donepezil could be related to its agonist effect on S1R.

It's unlikely that entire or even the majority of effect of DZP is related to its S1R effects given that other ACH-I's have similar effects and lack the S1R aspect.