The pooled data of population-based studies in Europe suggests that the age-standardized prevalence in people 65+ years old is 6.4 % for dementia and 4.4 % for AD.3 In the US, the study of a national representative sample of people aged >70 years yielded a prevalence for AD of 9.7 %. 4 Worldwide, the global prevalence of dementia was estimated to be 3.9 % in people aged 60+ years, with the regional prevalence being 1.6 % in Africa, 4.0 % in China and Western Pacific regions, 4.6 % in Latin America, 5.4 % in Western Europe, and 6.4 % in North America.5 More than 25 million people in the world are currently affected by dementia, most suffering from AD, with around 5 million new cases occurring every year.5-7 The number of people with dementia is anticipated to double every 20 years. Despite different inclusion criteria, several meta-analyses and nationwide surveys have yielded roughly similar age-specific prevalence of AD across regions (Figure 1).3,4,8,9 The age-specific prevalence of AD almost doubles every 5 years after aged 65. Among developed nations, approximately 1 in 10 older people (65+ years) is affected by some degree of dementia, whereas more than one third of very old people (85+ years) may have dementia-related symptoms and signs.10,11 There is a similar pattern of dementia subtypes across the world, with AD and vascular dementia, the two most common forms of dementia, accounting for 50 % to 70 % and 15 % to 25 %, respectively, of all dementia cases.
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