Replies to post #173503 on Anavex Life Sciences Corp (AVXL)

[XenaLives]

Yet there are biomarkers which are common to most, if not all, CNS disease.

Stress which creates inflammatory cytokine cascades..

Quality of sleep which is known to be necessary for neurological housekeeping.

These are the two that come to mind easily, there may be others.

Anavex 2-73 seems to create beneficial action in both of these. It is also safe..

So why on earth would approval be denied if there is improvement in these biomarkers?

There are complex systems of rhythms, hormones, emotions, all interacting, most of which have feedback loops into other systems/parts of the brain.

Agreed, but inflammation and lack of sleep is known to disrupt those systems.