Replies to post #197869 on NorthWest Biotherapeutics Inc (NWBO)

[jondoeuk]

In most cases, that's true. Of course a number of companies are trying to move beyond that. $IOVA entered into an agreement with $RXII. The former will use the latter's sd-rxRNA to enhance the tumour killing activity of TIL https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(18)30172-2

$GILD have a range of TCRs including neoantigen reactive and could use synNotch https://www.cell.com/cell/fulltext/S0092-8674(16)31244-2 or $SGMO (https://endpts.com/all-in-gilead-maps-a-3-15b-alliance-with-sangamo-for-off-the-shelf-car-t-drugs/) ZFNs https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)30173-3