not only was it lower risk, it was on japanese people who naturally have higher EPA in system...what were the age specs in reduce it though? jelis 70% of people were over 75 (females) so thats pretty old which may counteract the healthiness. with average person living to 82 in japan, and the fact females were all 80 when the study ended, that may have made death look higher...just playing devils advocate.
i still think we see a better CVD result than jelis, but this predicament has stumped me.
Strokes RRR won't be big, we know that, EPA does not seem to have a significant impact on strokes also from Jelis and other smaller trials. Strokes are more linked to BP Angina will not have much of an impact, since much more stringent requirements in RIT to classify as an event Revascularization RRR was not big in Jelis and we can assume it will be similar in RIT. IMO all is pointing to a big RRR in MI (fatal and not) and CVD deaths to offset lower RRR in other MACE's