Replies to post #36607 on Biotech Values

[DewDiligence]

>JP predicted no drug interaction problems NM283 and riba @ about 1.54 into the CC... In fact it was he who asked Dr Dieterich to comment.<

What goifish and I questioned was Dr Dieterich’s assertion that there would be no interaction problem in man because there was no interaction problem in the replicon. He just seemed a little too sure of himself on this (and other matters), which is not to say that gofish and I think there will be an interaction problem.

>what is replicon system?<

It’s a ex vivo model which permits HCV replication that is commonly used because HCV does not have a reliable small-animal model.