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Re: go seek post# 36607

Tuesday, 10/31/2006 6:00:58 AM

Tuesday, October 31, 2006 6:00:58 AM

Post# of 257268
>JP predicted no drug interaction problems NM283 and riba @ about 1.54 into the CC... In fact it was he who asked Dr Dieterich to comment.<

What goifish and I questioned was Dr Dieterich’s assertion that there would be no interaction problem in man because there was no interaction problem in the replicon. He just seemed a little too sure of himself on this (and other matters), which is not to say that gofish and I think there will be an interaction problem.

>what is replicon system?<

It’s a ex vivo model which permits HCV replication that is commonly used because HCV does not have a reliable small-animal model.

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