Thank you longfellow95 for the link and the follow-up to my surprise that this esteemed Dr. is also advising NWBO on manufacturing issues and processes. I imagine EX is correct and we cannot change the process to much, but others have noted we can to some extent. At least he is on board and will be able to advise us as time goes by and new trials are organized. Pretty complex this Bio Tech technology. Much more complicated than I ever imagined when I began investing in it 35 years ago. I know so much more now and realize I don't really know that much. I am thankful for you and so many contributors on this board and for those like Larry Smith and Boise who write articles. And that goes for Pyrr also. Peace Reg 2015