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Whalatane

08/19/18 11:27 PM

#220540 RE: Whalatane #220539

MDGL. follow up. I was hoping to see Lipid Data from MDGL's last trial presented at ESC Aug 25-29
......but it may not be til AASLD Nov 9-13

Anyone have any updates on this ?
Kiwi
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RockRat

08/20/18 9:32 AM

#220541 RE: Whalatane #220539

MDGL lipid data: Takes a little surfing to find the abstract, but yes, they are there with it (poster session 8/28 @ 830am in Germany).

MGL- 3196 Lipid Data ESC

As far as I can tell, it provides some numerical color and additional baseline characteristics, but otherwise, little has changed since February.

Regards, RockRat
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Bio_pete

08/20/18 1:06 PM

#220549 RE: Whalatane #220539

ESPR - LFT elevations are seen with every approved oral, once daily LDL-C lowering therapy. (.2% - 2.3%) Bempedoic acid has shown a confirmed rate of LFT elevations that is on the low-end of reported rates. (.49%)

LFT elevations with approved oral LDL-C lowering therapies & bempedoic acid have never been associated with serious liver injury

-No increases in bilirubin
-No cases of Hy's law


From 8-k ended 5/8/18