The question is valid and the answer/s are in plain sight -
1. Lack of progress - M is talking about A2-73 for so long without actually starting any new trial as promised
2. The trial size is very small with very inconclusive results - there is no confirmed MOA and confirm efficacy of whatever MOA co says
3. No BP or MP has shown confidence in the co by entering into any kind of collaboration
4. With reasons above - market does not believe anything M says - there is lack of credibility.
The lack of credibility, lack of high cash, lack of strong trial results and missing promised new trials - all are reflected in the current market cap
Do better execution, start new trial and start some believable strong results and SP will move in right direction.