None of us knows what feedback the FDA had on the Rett IND, but anyone is free to promote that it was something approaching a doomsday scenario
Let’s be clear, I never said it was a “doomsday scenario”.
I did suggest that the Rett girl’s communication difficulties in communicating side effects could complicate the IND application before it actually happened though.
Based on preclinical data, what dose would you predict they would like to use in the Rett trial? (I’ve asked several times now)