1) IV verses B-OM swish and spit. 2) long and frequent visits to administer IV verses B-OM swish and spit at home. 3) the regimen adds about $1500 per visit (could be up to $2400) to cost of onco therapy, for how many visits? 4) May not be covered by most insurers. 5) focus in report was on <60 Gy verses >60 Gy for B-OM with <55 Gy thrown out.
B-OM's result is better with stricter criteria IMO.
In addition they reported "in the overall incidence of SOM through 60 Gy of radiation" We reported "cumulative radiation dose criteria of at least 55 Gy—the minimum treatment threshold for inclusion in the efficacy population." So we made it more challenging for ourselves by using the lower number of 55GY.