1) IV verses B-OM swish and spit. 2) long and frequent visits to administer IV verses B-OM swish and spit at home. 3) the regimen adds about $1500 per visit (could be up to $2400) to cost of onco therapy, for how many visits? 4) May not be covered by most insurers. 5) focus in report was on <60 Gy verses >60 Gy for B-OM with <55 Gy thrown out.