Replies to post #127433 on Anavex Life Sciences Corp (AVXL)

[blu_1]

IDK. They prolly had 1 or 2 between 24 and 28 for MMSE. Maybe those patients had crappy Cogsate, ERP, P3a, Ham D, and ADCS ADL scores. Maybe the Ph 2A group had 20 patients out of 30 w/MMSE in the 16-20 range so the group skewed Mod AD. I'm confident only 1 or 2 were above 24. Since the majority were mod or mild, going by MMSE scores only, Anavex said the group as a whole was mild to mod. Maybe the avg and/or mean score for the group was about 20, so they called the group Mild to Mod.

What were the MMSE ranges for those other trials you're comparing to the Anavex trial? Did they have anyone with MMSE consistent with only MCI or pre-AD? Did everyone in those groups have MMSE's 20 and above?

Doesn't it impress you that in every pre clinical trial 2-73 is entered into, for multiple indications, it performs exceptionally well? That tells me it helps stabilize cells under stress.

[Steady_T]

If that was true that there were people that had 25 to 28 scores then it would be very difficult for 2-73 to show improvement for those people since that had little headroom to improve into.

One would suspect that the CT or MRI were more diagnostic than the MMSE.