Replies to post #138896 on NorthWest Biotherapeutics Inc (NWBO)

[Rootjim]

This is where modeling comes into play. Since this trial has gone on for so long the confusion begins. The American Brain Tumor Association has the 5 year survival rate for gbm at 10%. Although the last patients in NWBO trial were enrolled about 2 years ago. Many were enrolled more than two years ago, which would be a positive for the success of NWBO trial.

[biosectinvestor]

I think some substantial amount of the day-to-day trading in many of these stocks is market maker driven, moment-by-moment arbitrage of trading data, driven by machine trading algorithms. So you enter an order at .17 to buy, seeing it available at .17, but the computer swoops in and buys and and moves it up a bit on you... and as you re-enter your next order, it does the same, and lets you have it at .1704, and then drops it down again if there are no orders.

I think a lot of volume is driven by nonsense like that, which allows market makers to accumulate pennies that make them millions cumulatively.