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frrol

09/24/17 8:41 AM

#121463 RE: Steady_T #121448

It's always in the presentations, see the "Baseline Patient Characteristics" slide. Our trial patient population is about 50% APO4 carriers.

Some higher statistics here: This doesn't mean APO4 isn't correlated at all with effectiveness, just not as a solitary factor. It could be, for example, that the combination of gene X and APO4 is the effectiveness factor. But Anavex is not sophisticated enough to detect that themselves. Hence they hired Ariana.
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frrol

09/24/17 9:14 AM

#121465 RE: Steady_T #121448

I should add that the test for APO4 mutations is a simple and very quick test, which is why they tested for it for the trial. A no-brainer. I suspect it is done for all AD trials.