Replies to post #132647 on NorthWest Biotherapeutics Inc (NWBO)

[Tadasana]

Thanks alpha puppy, for the repost and quick response. Yeah like if barcode would of notified them that they had a lawsuit filed against them they could of responded in time before the default judgement. Barcode knew before they did of the lawsuit, but he assumed they knew and just did not respond, when actually they were not even aware of it cause their receptionist most likely signed for it and dropped it on their desk which they most likely never looked at, cause they don't go into the office that much but work from home, imho.

So goes to show you never assume anything with them. They wear too many hats and have trouble delegating because they have no one to delegate to... remember when LP had the flu and everything came to a stand still? I really appreciate all their hard work but there is just so much they can do with all that has to be done in a timely manner. So there is the perfect instance if barcode would let Les know he could of saved a lot of lawyer fees cause now they have to back track and plea with the judge for not responding in time.

I think your work would be helpful to present to institutions or BPs interested in financing them. Given the data and statistical significance. There is no doubt of efficacy. imho it would also help if they could get Dr.Liau to present with them, after all she is the principle investigator.

[marzan]

A very thorough analysis, great work! Your product proves you are a very good researcher. Enjoyed reading and convinced clearly DCVax L is going to be the Gold Standard - no doubt about it.

[Horseb4CarT]

Alpha puppy, did I not follow the math correctly where you have 311- 1x1 = 148 ? I used an x because I didn't remember the exact number, but I don't get 148 from the subtraction.

Otherwise your posted analysis is quite impressive and your conclusions are encouraging, to use a word that Dr. Bosch and LP seem to like.

This is my first post on ihub and I am long nwbo for years and waiting with mixed emotions like many here.

[anders2211]

alphapuppy, do you by any chance know how the FDA would react on trail terms not met (the 233 events) but statistically being superior to SOC?

Would the FDA, also with the 21-century act in mind, be a pain in the but and dismiss the trail only because it was ended before the events were met never minding it beats SOC in many ways?

thanks for answering

[exwannabe]

Alphapuppy, what do you think happened to the trial in Mid June of '15?

Per your model, all 11 patients randomized post 6/15 into the control arm were alive and progression free (as of the 2/'17 data cut) . While in the treatment arm, 21 of 28 (PFS) evented.

That is a large benefit towards the control arm, well past the bounds of random chance.

Did something happen to the trial back then?

[Tadasana]

CDRD, AP did repost, thanks.

[Doc logic]

alphapuppy,

Thanks for all your efforts here. You have demonstrated once again that the evidence is pointing to strong validation of treatment efficacy utilizing known data points of unblinded data. Best wishes.