NorthWest Biotherapeutics Inc (NWBO)

[alphapuppy]

REPOST with updated links

Data lock will equal a real date.

ie Say 9-1-2017 or whatever.

Then that date will be used as the "last date of Follow-up or Death" and the KM curves and all statistics will use that date to calculate the time factor (ie amount of time from a patients entry into the trial to the particular parameter measured such as progression or death or whatever is defined as an 'event'. Or if the patient has not experienced any event they will have a time factor = to the lock date minus their date of trial entry and randomization.

For patients that have not evented, they will be censored and not used for making the KM curve for any time that is greater than the difference of the lock date minus their particular data entry date or randomization date.

Please see this review and comparison of my PFS model results with the NEJM STUPP data. One can see how revolutionary this treatment will be as the STUPP protocol is arguably still the standard of Care (+/- Optune).

https://www.dropbox.com/s/ywsv4jyv7mkucxs/DCVacL%20compared%20to%20STUPP.JPG?dl=0

Also, note the Stupp gragh gives the number of patients at risk at various time intervals under the gragh so one knows how many patients data are left for the longer time periods out. IE those numbers below equal the total number of patients on the various trial arms minus those who have evented or who were censored.

For you to better understand this I include below the data I used to create the current model comparisons. So, in this case, the Date of entry is the dates given by Bosch at ASCO 2017 for the patient enrollment ramp. The treatment(1) or Placebo (2) was generated by a random number generator in excel in a 2 to 1 ratio for experimental and placebo respectively. Then the Control (0) group was manually given the time in days and the events directly based on the IMUC Control group data pro rata to compensate for the larger NWBO trial.

Then once the number of events were derived in the NWBO control group by this method, the number of events remaining was simply a subtraction of the number of PFS events that NWBO has given us on 2 separate occasions: Once in Dec 2013 66 PFS events for the whole group and another disclosed in Feb. 2017 or before when 248 events were disclosed.

Then the exact same process was used on the experimental patient group in that the events and time were placed in to be equal to the published IMUC control group KM PFS curves ... but here is the cool part ... the number of events was limited to 148 which was derived as noted above and by Dec 2013 only 66 events were placed prior to that date. Therefore there were significantly fewer events in the experimental DCVaxL arm than would have been expected had the experiment arm survived progression free at the same rate as was published by the IMUC control group curves.

Then it was a simple matter of inputting the time factor, the event/censor factor and the group placebo or experimental into the KM statistical software.

And walla the curves appear with the statistical comparison tests.

Derived Data for all 331 patients in the DCVax-L TRIAL

PT # * ENTRY * RX=1 Placebo=0 * DAYS * 1=event 0= censor * DATE EVENT or Censor * MONTHS * Plus 83d Mo
1 * 6/2/2008 * 1 * 53 * 1 * 7/25/2008 * 1.8 * 4.6
2 * 6/13/2008 * 0 * 53 * 1 * 8/5/2008 * 1.8 * 4.6
3 * 6/27/2008 * 1 * 53 * 1 * 8/19/2008 * 1.8 * 4.6
4 * 7/23/2008 * 0 * 53 * 1 * 9/14/2008 * 1.8 * 4.6
5 * 7/10/2008 * 1 * 85 * 1 * 10/3/2008 * 2.8 * 5.6
6 * 8/5/2008 * 0 * 85 * 1 * 10/29/2008 * 2.8 * 5.6
7 * 9/12/2008 * 1 * 85 * 1 * 12/6/2008 * 2.8 * 5.6
8 * 9/26/2008 * 1 * 95 * 1 * 12/30/2008 * 3.2 * 6
9 * 10/9/2008 * 1 * 95 * 1 * 1/12/2009 * 3.2 * 6
10 * 11/4/2008 * 0 * 85 * 1 * 1/28/2009 * 2.8 * 5.6
11 * 11/17/2008 * 0 * 95 * 1 * 2/20/2009 * 3.2 * 6
12 * 12/1/2008 * 0 * 95 * 1 * 3/6/2009 * 3.2 * 6
13 * 12/12/2008 * 0 * 105 * 1 * 3/27/2009 * 3.5 * 6.3
14 * 12/26/2008 * 0 * 105 * 1 * 4/10/2009 * 3.5 * 6.3
15 * 1/8/2009 * 0 * 112 * 1 * 4/30/2009 * 3.7 * 6.5
16 * 2/3/2009 * 1 * 105 * 1 * 5/19/2009 * 3.5 * 6.3
17 * 2/16/2009 * 1 * 105 * 1 * 6/1/2009 * 3.5 * 6.3
18 * 3/2/2009 * 0 * 112 * 1 * 6/22/2009 * 3.7 * 6.5
19 * 3/13/2009 * 0 * 112 * 1 * 7/3/2009 * 3.7 * 6.5
20 * 3/27/2009 * 0 * 112 * 1 * 7/17/2009 * 3.7 * 6.5
21 * 4/9/2009 * 1 * 112 * 1 * 7/30/2009 * 3.7 * 6.5
22 * 10/3/2011 * 0 * 120 * 1 * 1/31/2012 * 4 * 6.8
23 * 10/21/2011 * 0 * 120 * 1 * 2/18/2012 * 4 * 6.8
24 * 11/2/2011 * 0 * 120 * 1 * 3/1/2012 * 4 * 6.8
25 * 11/14/2011 * 1 * 112 * 1 * 3/5/2012 * 3.7 * 6.5
26 * 11/24/2011 * 0 * 120 * 1 * 3/23/2012 * 4 * 6.8
27 * 12/5/2011 * 0 * 120 * 1 * 4/3/2012 * 4 * 6.8
28 * 12/15/2011 * 1 * 112 * 1 * 4/5/2012 * 3.7 * 6.5
29 * 12/26/2011 * 1 * 112 * 1 * 4/16/2012 * 3.7 * 6.5
30 * 1/6/2012 * 0 * 120 * 1 * 5/5/2012 * 4 * 6.8
31 * 2/7/2012 * 0 * 122 * 1 * 6/8/2012 * 4.1 * 6.9
32 * 2/17/2012 * 1 * 120 * 1 * 6/16/2012 * 4 * 6.8
33 * 2/29/2012 * 0 * 122 * 1 * 6/30/2012 * 4.1 * 6.9
34 * 3/11/2012 * 1 * 120 * 1 * 7/9/2012 * 4 * 6.8
35 * 3/21/2012 * 1 * 120 * 1 * 7/19/2012 * 4 * 6.8
36 * 4/1/2012 * 0 * 123 * 1 * 8/2/2012 * 4.1 * 6.9
37 * 5/4/2012 * 0 * 123 * 1 * 9/4/2012 * 4.1 * 6.9
38 * 5/14/2012 * 1 * 120 * 1 * 9/11/2012 * 4 * 6.8
39 * 5/25/2012 * 1 * 120 * 1 * 9/22/2012 * 4 * 6.8
40 * 6/5/2012 * 0 * 126 * 1 * 10/9/2012 * 4.2 * 7
41 * 6/16/2012 * 1 * 120 * 1 * 10/14/2012 * 4 * 6.8
42 * 6/27/2012 * 0 * 126 * 1 * 10/31/2012 * 4.2 * 7
43 * 8/20/2012 * 1 * 122 * 1 * 12/20/2012 * 4.1 * 6.9
44 * 7/29/2012 * 0 * 151 * 1 * 12/27/2012 * 5 * 7.8
45 * 8/9/2012 * 0 * 151 * 1 * 1/7/2013 * 5 * 7.8
46 * 9/10/2012 * 1 * 122 * 1 * 1/10/2013 * 4.1 * 6.9
47 * 9/21/2012 * 1 * 123 * 1 * 1/22/2013 * 4.1 * 6.9
48 * 8/30/2012 * 0 * 158 * 1 * 2/4/2013 * 5.3 * 8.1
49 * 11/3/2012 * 1 * 123 * 1 * 3/6/2013 * 4.1 * 6.9
50 * 11/14/2012 * 1 * 126 * 1 * 3/20/2013 * 4.2 * 7
51 * 10/23/2012 * 0 * 158 * 1 * 3/30/2013 * 5.3 * 8.1
52 * 12/16/2012 * 1 * 126 * 1 * 4/21/2013 * 4.2 * 7
53 * 11/25/2012 * 0 * 158 * 1 * 5/2/2013 * 5.3 * 8.1
54 * 12/6/2012 * 0 * 172 * 1 * 5/27/2013 * 5.7 * 8.5
55 * 1/18/2013 * 1 * 151 * 1 * 6/18/2013 * 5 * 7.8
56 * 1/29/2013 * 1 * 151 * 1 * 6/29/2013 * 5 * 7.8
57 * 2/8/2013 * 1 * 158 * 1 * 7/16/2013 * 5.3 * 8.1
58 * 2/19/2013 * 0 * 172 * 1 * 8/10/2013 * 5.7 * 8.5
59 * 3/2/2013 * 0 * 172 * 1 * 8/21/2013 * 5.7 * 8.5
60 * 4/3/2013 * 1 * 158 * 1 * 9/8/2013 * 5.3 * 8.1
61 * 4/25/2013 * 1 * 158 * 1 * 9/30/2013 * 5.3 * 8.1
62 * 4/14/2013 * 0 * 175 * 1 * 10/6/2013 * 5.8 * 8.6
63 * 5/6/2013 * 0 * 175 * 1 * 10/28/2013 * 5.8 * 8.6
64 * 5/15/2013 * 0 * 182 * 1 * 11/13/2013 * 6.1 * 8.9
65 * 5/30/2013 * 1 * 172 * 1 * 11/18/2013 * 5.7 * 8.5
66 * 5/26/2013 * 0 * 182 * 1 * 11/24/2013 * 6.1 * 8.9
67 * 6/13/2013 * 1 * 172 * 1 * 12/2/2013 * 5.7 * 8.5
68 * 6/17/2013 * 1 * 172 * 1 * 12/6/2013 * 5.7 * 8.5
69 * 6/22/2013 * 1 * 175 * 1 * 12/14/2013 * 5.8 * 8.6
70 * 7/5/2013 * 1 * 175 * 1 * 12/27/2013 * 5.8 * 8.6
71 * 7/14/2013 * 1 * 182 * 1 * 1/12/2014 * 6.1 * 8.9
72 * 7/19/2013 * 1 * 182 * 1 * 1/17/2014 * 6.1 * 8.9
73 * 7/10/2013 * 0 * 200 * 1 * 1/26/2014 * 6.7 * 9.5
74 * 7/23/2013 * 0 * 200 * 1 * 2/8/2014 * 6.7 * 9.5
75 * 8/6/2013 * 1 * 200 * 1 * 2/22/2014 * 6.7 * 9.5
76 * 8/15/2013 * 1 * 200 * 1 * 3/3/2014 * 6.7 * 9.5
77 * 8/10/2013 * 0 * 206 * 1 * 3/4/2014 * 6.9 * 9.7
78 * 8/19/2013 * 1 * 206 * 1 * 3/13/2014 * 6.9 * 9.7
79 * 9/2/2013 * 1 * 206 * 1 * 3/27/2014 * 6.9 * 9.7
80 * 9/7/2013 * 0 * 206 * 1 * 4/1/2014 * 6.9 * 9.7
81 * 9/11/2013 * 1 * 210 * 1 * 4/9/2014 * 7 * 9.8
82 * 9/16/2013 * 1 * 210 * 1 * 4/14/2014 * 7 * 9.8
83 * 9/20/2013 * 0 * 210 * 1 * 4/18/2014 * 7 * 9.8
84 * 10/13/2013 * 0 * 210 * 1 * 5/11/2014 * 7 * 9.8
85 * 10/4/2013 * 1 * 224 * 1 * 5/16/2014 * 7.5 * 10.3
86 * 10/8/2013 * 1 * 224 * 1 * 5/20/2014 * 7.5 * 10.3
87 * 10/17/2013 * 0 * 224 * 1 * 5/29/2014 * 7.5 * 10.3
88 * 10/22/2013 * 0 * 224 * 1 * 6/3/2014 * 7.5 * 10.3
89 * 10/26/2013 * 1 * 260 * 1 * 7/13/2014 * 8.7 * 11.5
90 * 11/9/2013 * 1 * 260 * 1 * 7/27/2014 * 8.7 * 11.5
91 * 11/13/2013 * 1 * 278 * 1 * 8/18/2014 * 9.3 * 12.1
92 * 11/18/2013 * 1 * 278 * 1 * 8/23/2014 * 9.3 * 12.1
93 * 12/15/2013 * 0 * 260 * 1 * 9/1/2014 * 8.7 * 11.5
94 * 12/2/2013 * 1 * 290 * 1 * 9/18/2014 * 9.7 * 12.5
95 * 4/21/2014 * 1 * 151 * 1 * 9/19/2014 * 5 * 7.8
96 * 12/6/2013 * 1 * 290 * 1 * 9/22/2014 * 9.7 * 12.5
97 * 12/11/2013 * 1 * 300 * 1 * 10/7/2014 * 10 * 12.8
98 * 1/20/2014 * 0 * 260 * 1 * 10/7/2014 * 8.7 * 11.5
99 * 5/4/2014 * 1 * 158 * 1 * 10/9/2014 * 5.3 * 8.1
100 * 5/13/2014 * 1 * 158 * 1 * 10/18/2014 * 5.3 * 8.1
101 * 8/31/2014 * 1 * 53 * 1 * 10/23/2014 * 1.8 * 4.6
102 * 9/3/2014 * 1 * 53 * 1 * 10/26/2014 * 1.8 * 4.6
103 * 1/25/2014 * 0 * 278 * 1 * 10/30/2014 * 9.3 * 12.1
104 * 12/29/2013 * 1 * 312 * 1 * 11/6/2014 * 10.4 * 13.2
105 * 5/18/2014 * 1 * 172 * 1 * 11/6/2014 * 5.7 * 8.5
106 * 1/2/2014 * 1 * 315 * 1 * 11/13/2014 * 10.5 * 13.3
107 * 6/1/2014 * 1 * 172 * 1 * 11/20/2014 * 5.7 * 8.5
108 * 1/7/2014 * 1 * 318 * 1 * 11/21/2014 * 10.6 * 13.4
109 * 6/6/2014 * 1 * 175 * 1 * 11/28/2014 * 5.8 * 8.6
110 * 3/2/2014 * 0 * 278 * 1 * 12/5/2014 * 9.3 * 12.1
111 * 9/12/2014 * 1 * 85 * 1 * 12/6/2014 * 2.8 * 5.6
112 * 6/18/2014 * 1 * 182 * 1 * 12/17/2014 * 6.1 * 8.9
113 * 1/29/2014 * 1 * 322 * 1 * 12/17/2014 * 10.7 * 13.5
114 * 2/3/2014 * 1 * 321 * 1 * 12/21/2014 * 10.7 * 13.5
115 * 2/7/2014 * 1 * 323 * 1 * 12/27/2014 * 10.8 * 13.6
116 * 9/24/2014 * 1 * 95 * 1 * 12/28/2014 * 3.2 * 6
117 * 3/16/2014 * 0 * 290 * 1 * 12/31/2014 * 9.7 * 12.5
118 * 3/25/2014 * 0 * 290 * 1 * 1/9/2015 * 9.7 * 12.5
119 * 2/21/2014 * 1 * 324 * 1 * 1/11/2015 * 10.8 * 13.6
120 * 2/25/2014 * 1 * 323 * 1 * 1/14/2015 * 10.8 * 13.6
121 * 10/2/2014 * 1 * 105 * 1 * 1/15/2015 * 3.5 * 6.3
122 * 10/5/2014 * 1 * 105 * 1 * 1/18/2015 * 3.5 * 6.3
123 * 3/7/2014 * 1 * 320 * 1 * 1/21/2015 * 10.7 * 13.5
124 * 10/11/2014 * 1 * 112 * 1 * 1/31/2015 * 3.7 * 6.5
125 * 4/12/2014 * 0 * 300 * 1 * 2/6/2015 * 10 * 12.8
126 * 3/29/2014 * 1 * 325 * 1 * 2/17/2015 * 10.8 * 13.6
127 * 4/3/2014 * 1 * 325 * 1 * 2/22/2015 * 10.8 * 13.6
128 * 4/30/2014 * 0 * 300 * 1 * 2/24/2015 * 10 * 12.8
129 * 11/4/2014 * 1 * 112 * 1 * 2/24/2015 * 3.7 * 6.5
130 * 4/7/2014 * 1 * 325 * 1 * 2/26/2015 * 10.8 * 13.6
131 * 11/7/2014 * 1 * 120 * 1 * 3/7/2015 * 4 * 6.8
132 * 11/13/2014 * 1 * 120 * 1 * 3/13/2015 * 4 * 6.8
133 * 5/9/2014 * 0 * 310 * 1 * 3/15/2015 * 10.3 * 13.1
134 * 11/25/2014 * 1 * 120 * 1 * 3/25/2015 * 4 * 6.8
135 * 10/26/2014 * 0 * 151 * 1 * 3/26/2015 * 5 * 7.8
136 * 10/29/2014 * 0 * 151 * 1 * 3/29/2015 * 5 * 7.8
137 * 5/22/2014 * 0 * 312 * 1 * 3/30/2015 * 10.4 * 13.2
138 * 12/3/2014 * 1 * 120 * 1 * 4/2/2015 * 4 * 6.8
139 * 12/6/2014 * 1 * 122 * 1 * 4/7/2015 * 4.1 * 6.9
140 * 11/1/2014 * 0 * 158 * 1 * 4/8/2015 * 5.3 * 8.1
141 * 12/9/2014 * 1 * 122 * 1 * 4/10/2015 * 4.1 * 6.9
142 * 11/10/2014 * 0 * 158 * 1 * 4/17/2015 * 5.3 * 8.1
143 * 12/18/2014 * 1 * 123 * 1 * 4/20/2015 * 4.1 * 6.9
144 * 6/9/2014 * 0 * 315 * 1 * 4/20/2015 * 10.5 * 13.3
145 * 11/19/2014 * 0 * 158 * 1 * 4/26/2015 * 5.3 * 8.1
146 * 6/12/2014 * 0 * 318 * 1 * 4/26/2015 * 10.6 * 13.4
147 * 6/15/2014 * 0 * 319 * 1 * 4/30/2015 * 10.6 * 13.4
148 * 12/27/2014 * 1 * 126 * 1 * 5/2/2015 * 4.2 * 7
149 * 11/22/2014 * 0 * 172 * 1 * 5/13/2015 * 5.7 * 8.5
150 * 12/1/2014 * 0 * 172 * 1 * 5/22/2015 * 5.7 * 8.5
151 * 7/6/2014 * 0 * 320 * 1 * 5/22/2015 * 10.7 * 13.5
152 * 12/30/2014 * 1 * 151 * 1 * 5/30/2015 * 5 * 7.8
153 * 7/15/2014 * 0 * 322 * 1 * 6/2/2015 * 10.7 * 13.5
154 * 1/5/2015 * 1 * 151 * 1 * 6/5/2015 * 5 * 7.8
155 * 12/15/2014 * 0 * 172 * 1 * 6/5/2015 * 5.7 * 8.5
156 * 7/24/2014 * 0 * 321 * 1 * 6/10/2015 * 10.7 * 13.5
157 * 7/27/2014 * 0 * 323 * 1 * 6/15/2015 * 10.8 * 13.6
158 * 12/24/2014 * 0 * 175 * 1 * 6/17/2015 * 5.8 * 8.6
159 * 1/14/2015 * 1 * 158 * 1 * 6/21/2015 * 5.3 * 8.1
160 * 1/2/2015 * 0 * 175 * 1 * 6/26/2015 * 5.8 * 8.6
161 * 6/21/2014 * 1 * 380 * 1 * 7/6/2015 * 12.7 * 15.5
162 * 1/8/2015 * 0 * 182 * 1 * 7/9/2015 * 6.1 * 8.9
163 * 6/27/2014 * 1 * 380 * 1 * 7/12/2015 * 12.7 * 15.5
164 * 1/26/2015 * 1 * 172 * 1 * 7/17/2015 * 5.7 * 8.5
165 * 8/28/2014 * 0 * 324 * 1 * 7/18/2015 * 10.8 * 13.6
166 * 1/29/2015 * 1 * 172 * 1 * 7/20/2015 * 5.7 * 8.5
167 * 2/1/2015 * 1 * 172 * 1 * 7/23/2015 * 5.7 * 8.5
168 * 9/6/2014 * 0 * 324 * 1 * 7/27/2015 * 10.8 * 13.6
169 * 7/3/2014 * 1 * 390 * 1 * 7/28/2015 * 13 * 15.8
170 * 9/18/2014 * 0 * 320 * 1 * 8/4/2015 * 10.7 * 13.5
171 * 9/15/2014 * 0 * 323 * 1 * 8/4/2015 * 10.8 * 13.6
172 * 2/13/2015 * 1 * 175 * 1 * 8/7/2015 * 5.8 * 8.6
173 * 9/27/2014 * 0 * 320 * 1 * 8/13/2015 * 10.7 * 13.5
174 * 9/30/2014 * 0 * 325 * 1 * 8/21/2015 * 10.8 * 13.6
175 * 2/25/2015 * 1 * 182 * 1 * 8/26/2015 * 6.1 * 8.9
176 * 10/17/2014 * 0 * 325 * 1 * 9/7/2015 * 10.8 * 13.6
177 * 10/20/2014 * 0 * 325 * 1 * 9/10/2015 * 10.8 * 13.6
178 * 7/9/2014 * 1 * 430 * 1 * 9/12/2015 * 14.3 * 17.1
179 * 10/23/2014 * 0 * 325 * 1 * 9/13/2015 * 10.8 * 13.6
180 * 7/12/2014 * 1 * 430 * 1 * 9/15/2015 * 14.3 * 17.1
181 * 3/3/2015 * 1 * 200 * 1 * 9/19/2015 * 6.7 * 9.5
182 * 3/6/2015 * 1 * 200 * 1 * 9/22/2015 * 6.7 * 9.5
183 * 7/21/2014 * 1 * 435 * 1 * 9/29/2015 * 14.5 * 17.3
184 * 3/15/2015 * 1 * 206 * 1 * 10/7/2015 * 6.9 * 9.7
185 * 8/1/2014 * 1 * 440 * 1 * 10/15/2015 * 14.7 * 17.5
186 * 3/21/2015 * 1 * 210 * 1 * 10/17/2015 * 7 * 9.8
187 * 3/24/2015 * 1 * 224 * 1 * 11/3/2015 * 7.5 * 10.3
188 * 3/27/2015 * 1 * 224 * 1 * 11/6/2015 * 7.5 * 10.3
189 * 8/4/2014 * 1 * 470 * 1 * 11/17/2015 * 15.7 * 18.5
190 * 8/7/2014 * 1 * 470 * 1 * 11/20/2015 * 15.7 * 18.5
191 * 8/16/2014 * 1 * 480 * 1 * 12/9/2015 * 16 * 18.8
192 * 4/8/2015 * 1 * 260 * 1 * 12/24/2015 * 8.7 * 11.5
193 * 7/28/2015 * 1 * 151 * 1 * 12/26/2015 * 5 * 7.8
194 * 8/3/2015 * 1 * 158 * 1 * 1/8/2016 * 5.3 * 8.1
195 * 8/9/2015 * 1 * 158 * 1 * 1/14/2016 * 5.3 * 8.1
196 * 4/17/2015 * 1 * 278 * 1 * 1/20/2016 * 9.3 * 12.1
197 * 8/19/2014 * 1 * 520 * 1 * 1/21/2016 * 17.3 * 20.1
198 * 1/20/2015 * 0 * 380 * 1 * 2/4/2016 * 12.7 * 15.5
199 * 4/23/2015 * 1 * 290 * 1 * 2/7/2016 * 9.7 * 12.5
200 * 1/23/2015 * 0 * 380 * 1 * 2/7/2016 * 12.7 * 15.5
201 * 4/26/2015 * 1 * 290 * 1 * 2/10/2016 * 9.7 * 12.5
202 * 2/7/2015 * 0 * 380 * 1 * 2/22/2016 * 12.7 * 15.5
203 * 5/2/2015 * 1 * 300 * 1 * 2/26/2016 * 10 * 12.8
204 * 2/10/2015 * 0 * 390 * 1 * 3/6/2016 * 13 * 15.8
205 * 2/16/2015 * 0 * 390 * 1 * 3/12/2016 * 13 * 15.8
206 * 5/8/2015 * 1 * 312 * 1 * 3/15/2016 * 10.4 * 13.2
207 * 5/11/2015 * 1 * 315 * 1 * 3/21/2016 * 10.5 * 13.3
208 * 5/14/2015 * 1 * 318 * 1 * 3/27/2016 * 10.6 * 13.4
209 * 5/26/2015 * 1 * 320 * 1 * 4/10/2016 * 10.7 * 13.5
210 * 6/7/2015 * 1 * 321 * 1 * 4/23/2016 * 10.7 * 13.5
211 * 2/19/2015 * 0 * 430 * 1 * 4/24/2016 * 14.3 * 17.1
212 * 2/28/2015 * 0 * 430 * 1 * 5/3/2016 * 14.3 * 17.1
213 * 6/16/2015 * 1 * 324 * 1 * 5/5/2016 * 10.8 * 13.6
214 * 6/22/2015 * 1 * 324 * 1 * 5/11/2016 * 10.8 * 13.6
215 * 6/28/2015 * 1 * 320 * 1 * 5/13/2016 * 10.7 * 13.5
216 * 3/9/2015 * 0 * 435 * 1 * 5/17/2016 * 14.5 * 17.3
217 * 7/13/2015 * 1 * 325 * 1 * 6/2/2016 * 10.8 * 13.6
218 * 7/16/2015 * 1 * 325 * 1 * 6/5/2016 * 10.8 * 13.6
219 * 3/30/2015 * 0 * 435 * 1 * 6/7/2016 * 14.5 * 17.3
220 * 7/19/2015 * 1 * 325 * 1 * 6/8/2016 * 10.8 * 13.6
221 * 4/2/2015 * 0 * 440 * 1 * 6/15/2016 * 14.7 * 17.5
222 * 4/14/2015 * 0 * 440 * 1 * 6/27/2016 * 14.7 * 17.5
223 * 4/20/2015 * 0 * 470 * 1 * 8/2/2016 * 15.7 * 18.5
224 * 8/12/2015 * 1 * 380 * 1 * 8/26/2016 * 12.7 * 15.5
225 * 5/17/2015 * 0 * 470 * 1 * 8/29/2016 * 15.7 * 18.5
226 * 8/25/2014 * 1 * 740 * 1 * 9/3/2016 * 24.7 * 27.5
227 * 5/23/2015 * 0 * 480 * 1 * 9/14/2016 * 16 * 18.8
228 * 8/24/2015 * 1 * 390 * 1 * 9/17/2016 * 13 * 15.8
229 * 5/29/2015 * 0 * 480 * 1 * 9/20/2016 * 16 * 18.8
230 * 8/27/2015 * 1 * 390 * 1 * 9/20/2016 * 13 * 15.8
231 * 6/1/2015 * 0 * 520 * 1 * 11/2/2016 * 17.3 * 20.1
232 * 8/30/2015 * 1 * 430 * 1 * 11/2/2016 * 14.3 * 17.1
233 * 9/5/2015 * 1 * 435 * 1 * 11/13/2016 * 14.5 * 17.3
234 * 9/11/2015 * 1 * 440 * 1 * 11/24/2016 * 14.7 * 17.5
235 * 9/14/2015 * 1 * 440 * 1 * 11/27/2016 * 14.7 * 17.5
236 * 9/17/2015 * 1 * 470 * 1 * 12/30/2016 * 15.7 * 18.5
237 * 9/29/2015 * 1 * 480 * 1 * 1/21/2017 * 16 * 18.8
238 * 8/13/2014 * 0 * 902.2048193 * 1 * 2/1/2017 * 30.1 * 32.9
239 * 10/5/2015 * 0 * 485 * 0 * 2/1/2017 * 16.2 * 19
240 * 9/23/2015 * 0 * 497 * 0 * 2/1/2017 * 16.6 * 19.4
241 * 9/20/2015 * 0 * 500 * 0 * 2/1/2017 * 16.7 * 19.5
242 * 8/21/2015 * 0 * 530 * 0 * 2/1/2017 * 17.7 * 20.5
243 * 8/18/2015 * 0 * 533 * 0 * 2/1/2017 * 17.8 * 20.6
244 * 8/6/2015 * 0 * 545 * 0 * 2/1/2017 * 18.2 * 21
245 * 7/22/2015 * 0 * 560 * 0 * 2/1/2017 * 18.7 * 21.5
246 * 7/10/2015 * 0 * 572 * 0 * 2/1/2017 * 19.1 * 21.9
247 * 7/7/2015 * 0 * 575 * 0 * 2/1/2017 * 19.2 * 22
248 * 7/4/2015 * 0 * 578 * 0 * 2/1/2017 * 19.3 * 22.1
249 * 6/19/2015 * 0 * 593 * 0 * 2/1/2017 * 19.8 * 22.6
250 * 6/4/2013 * 1 * 1337.95122 * 1 * 2/1/2017 * 44.6 * 47.4
251 * 6/3/2014 * 1 * 973.0481928 * 1 * 2/1/2017 * 32.4 * 35.2
252 * 11/16/2014 * 1 * 807.746988 * 1 * 2/1/2017 * 26.9 * 29.7
253 * 2/22/2015 * 1 * 710 * 1 * 2/1/2017 * 23.7 * 26.5
254 * 4/11/2015 * 1 * 662 * 1 * 2/1/2017 * 22.1 * 24.9
255 * 7/25/2015 * 1 * 557 * 1 * 2/1/2017 * 18.6 * 21.4
256 * 10/2/2015 * 1 * 488 * 1 * 2/1/2017 * 16.3 * 19.1
257 * 8/18/2008 * 1 * 3089 * 0 * 2/1/2017 * 103 * 105.8
258 * 9/1/2008 * 1 * 3075 * 0 * 2/1/2017 * 102.5 * 105.3
259 * 10/22/2008 * 1 * 3024 * 0 * 2/1/2017 * 100.8 * 103.6
260 * 1/21/2009 * 1 * 2933 * 0 * 2/1/2017 * 97.8 * 100.6
261 * 4/15/2009 * 1 * 2849 * 0 * 2/1/2017 * 95 * 97.8
262 * 10/11/2011 * 1 * 1939.2 * 0 * 2/1/2017 * 64.6 * 67.4
263 * 1/17/2012 * 1 * 1842 * 0 * 2/1/2017 * 61.4 * 64.2
264 * 1/27/2012 * 1 * 1831.2 * 0 * 2/1/2017 * 61 * 63.8
265 * 4/12/2012 * 1 * 1755.6 * 0 * 2/1/2017 * 58.5 * 61.3
266 * 4/23/2012 * 1 * 1744.8 * 0 * 2/1/2017 * 58.2 * 61
267 * 7/7/2012 * 1 * 1669.2 * 0 * 2/1/2017 * 55.6 * 58.4
268 * 7/18/2012 * 1 * 1658.4 * 0 * 2/1/2017 * 55.3 * 58.1
269 * 10/2/2012 * 1 * 1582.8 * 0 * 2/1/2017 * 52.8 * 55.6
270 * 10/13/2012 * 1 * 1572 * 0 * 2/1/2017 * 52.4 * 55.2
271 * 12/27/2012 * 1 * 1496.4 * 0 * 2/1/2017 * 49.9 * 52.7
272 * 1/7/2013 * 1 * 1485.6 * 0 * 2/1/2017 * 49.5 * 52.3
273 * 3/13/2013 * 1 * 1420.8 * 0 * 2/1/2017 * 47.4 * 50.2
274 * 3/24/2013 * 1 * 1410 * 0 * 2/1/2017 * 47 * 49.8
275 * 6/8/2013 * 1 * 1333.426829 * 0 * 2/1/2017 * 44.4 * 47.2
276 * 6/26/2013 * 1 * 1315.329268 * 0 * 2/1/2017 * 43.8 * 46.6
277 * 7/1/2013 * 1 * 1310.804878 * 0 * 2/1/2017 * 43.7 * 46.5
278 * 7/28/2013 * 1 * 1283.658537 * 0 * 2/1/2017 * 42.8 * 45.6
279 * 8/1/2013 * 1 * 1279.134146 * 0 * 2/1/2017 * 42.6 * 45.4
280 * 8/24/2013 * 1 * 1256.512195 * 0 * 2/1/2017 * 41.9 * 44.7
281 * 8/29/2013 * 1 * 1251.987805 * 0 * 2/1/2017 * 41.7 * 44.5
282 * 9/25/2013 * 1 * 1224.841463 * 0 * 2/1/2017 * 40.8 * 43.6
283 * 9/29/2013 * 1 * 1220.317073 * 0 * 2/1/2017 * 40.7 * 43.5
284 * 10/31/2013 * 1 * 1188.646341 * 0 * 2/1/2017 * 39.6 * 42.4
285 * 11/4/2013 * 1 * 1184.121951 * 0 * 2/1/2017 * 39.5 * 42.3
286 * 11/22/2013 * 1 * 1166.02439 * 0 * 2/1/2017 * 38.9 * 41.7
287 * 11/27/2013 * 1 * 1161.5 * 0 * 2/1/2017 * 38.7 * 41.5
288 * 12/20/2013 * 1 * 1138.878049 * 0 * 2/1/2017 * 38 * 40.8
289 * 12/24/2013 * 1 * 1134.353659 * 0 * 2/1/2017 * 37.8 * 40.6
290 * 1/11/2014 * 1 * 1116.256098 * 0 * 2/1/2017 * 37.2 * 40
291 * 1/16/2014 * 1 * 1111.731707 * 0 * 2/1/2017 * 37.1 * 39.9
292 * 2/12/2014 * 1 * 1084.585366 * 0 * 2/1/2017 * 36.2 * 39
293 * 2/16/2014 * 1 * 1080.060976 * 0 * 2/1/2017 * 36 * 38.8
294 * 3/11/2014 * 1 * 1057.439024 * 0 * 2/1/2017 * 35.2 * 38
295 * 3/20/2014 * 1 * 1048.390244 * 0 * 2/1/2017 * 34.9 * 37.7
296 * 4/16/2014 * 1 * 1021.243902 * 0 * 2/1/2017 * 34 * 36.8
297 * 4/25/2014 * 1 * 1012.195122 * 0 * 2/1/2017 * 33.7 * 36.5
298 * 5/27/2014 * 1 * 980.5243902 * 0 * 2/1/2017 * 32.7 * 35.5
299 * 6/24/2014 * 1 * 952.3855422 * 0 * 2/1/2017 * 31.7 * 34.5
300 * 6/30/2014 * 1 * 946.4819277 * 0 * 2/1/2017 * 31.5 * 34.3
301 * 7/18/2014 * 1 * 928.7710843 * 0 * 2/1/2017 * 31 * 33.8
302 * 7/30/2014 * 1 * 916.9638554 * 0 * 2/1/2017 * 30.6 * 33.4
303 * 8/10/2014 * 1 * 905.1566265 * 0 * 2/1/2017 * 30.2 * 33
304 * 8/22/2014 * 1 * 893.3493976 * 0 * 2/1/2017 * 29.8 * 32.6
305 * 9/9/2014 * 1 * 875.6385542 * 0 * 2/1/2017 * 29.2 * 32
306 * 9/21/2014 * 1 * 863.8313253 * 0 * 2/1/2017 * 28.8 * 31.6
307 * 10/8/2014 * 1 * 846.1204819 * 0 * 2/1/2017 * 28.2 * 31
308 * 10/14/2014 * 1 * 840.2168675 * 0 * 2/1/2017 * 28 * 30.8
309 * 11/28/2014 * 1 * 795.939759 * 0 * 2/1/2017 * 26.5 * 29.3
310 * 12/12/2014 * 1 * 781.1807229 * 0 * 2/1/2017 * 26 * 28.8
311 * 12/21/2014 * 1 * 772.3253012 * 0 * 2/1/2017 * 25.7 * 28.5
312 * 1/11/2015 * 1 * 751.6626506 * 0 * 2/1/2017 * 25.1 * 27.9
313 * 1/17/2015 * 1 * 745.7590361 * 0 * 2/1/2017 * 24.9 * 27.7
314 * 2/4/2015 * 1 * 728 * 0 * 2/1/2017 * 24.3 * 27.1
315 * 3/12/2015 * 1 * 692 * 0 * 2/1/2017 * 23.1 * 25.9
316 * 3/18/2015 * 1 * 686 * 0 * 2/1/2017 * 22.9 * 25.7
317 * 4/5/2015 * 1 * 668 * 0 * 2/1/2017 * 22.3 * 25.1
318 * 4/29/2015 * 1 * 644 * 0 * 2/1/2017 * 21.5 * 24.3
319 * 5/5/2015 * 1 * 638 * 0 * 2/1/2017 * 21.3 * 24.1
320 * 5/20/2015 * 1 * 623 * 0 * 2/1/2017 * 20.8 * 23.6
321 * 6/4/2015 * 1 * 608 * 0 * 2/1/2017 * 20.3 * 23.1
322 * 6/25/2015 * 1 * 587 * 0 * 2/1/2017 * 19.6 * 22.4
323 * 7/1/2015 * 1 * 581 * 0 * 2/1/2017 * 19.4 * 22.2
324 * 7/31/2015 * 1 * 551 * 0 * 2/1/2017 * 18.4 * 21.2
325 * 8/15/2015 * 1 * 536 * 0 * 2/1/2017 * 17.9 * 20.7
326 * 9/2/2015 * 1 * 518 * 0 * 2/1/2017 * 17.3 * 20.1
327 * 9/8/2015 * 1 * 512 * 0 * 2/1/2017 * 17.1 * 19.9
328 * 9/26/2015 * 1 * 494 * 0 * 2/1/2017 * 16.5 * 19.3
329 * 6/10/2015 * 0 * 610 * 1 * 2/9/2017 * 20.3 * 23.1
330 * 6/13/2015 * 0 * 740 * 1 * 6/22/2017 * 24.7 * 27.5
331 * 10/15/2015 * 1 * 740 * 1 * 10/24/2017 * 24.7 * 27.5