"Just to underscore why in the proper context the P300 data seems encouraging and this concern seems off base. "
A clinical study published in 2015 on P300 and Alzheimer's disease is just the latest demonstrating your point.
"A clinical trial to validate event-related potential markers of Alzheimer's disease in outpatient settings "
Results
Subjects with mild AD showed lower amplitude and increased latency for ERP features associated with attention, working memory, and executive function. These subjects also had decreased accuracy and longer reaction time in the target detection task associated with the ERP test.
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