Replies to post #99924 on Anavex Life Sciences Corp (AVXL)

[MycroftHolmes]

RE: P300

The issue I've been discussing is whether the P300 can be used to assess drug effects. Thus far they have only been able to show that for latency.

I do not believe this statement to be accurate.

There are studies tracking the P300 Amplitude of Donepezil against healthy controls. Donepezil has been shown to increase amplitude in AD patients.

A2-73 data shows both an earlier and larger increase than the Donepezil studies which is why they are touting it in their slides.

I'd be pleased to have latency data as well but I am not sure what the issue is here.

Cheers

Mycroft