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gym gravity

08/28/06 1:34 PM

#597 RE: DewDiligence #596

Two birds with one stone, right?

Anti-thrombin acting on two different pathways is like knocking down two birds with one stone.

The converse scenario would be to knock a bird down, pick up the stone again and hit it a second time. Clearly not as effective.
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croumagnon

08/28/06 4:45 PM

#598 RE: DewDiligence #596

"the pathways inherent in these two disease components do not overlap."

Interesting article indeed but I am not sure if it is a positive or a negative for GTCB. Are you infering that ATryn has the potential to act as an anti-inflamatory agent as well as an anti-coagulation agent using two different pathways, or are you saying that the promise of ATryn in sepsis may not be as remarkable as once thought because it will have no effect on the inflamatory process? In other words, is the anti-inflamatory potential of ATryn in sepsis establishhed or is it merely a conjecture?