Agree that speculation factor may be gone to some extent, but R-It positive results means a sea change in the perception of this stock. Psychologically, there will be many investors that will buy AMRN on positive results based on desire to get in on ground floor before the earnings ramp you mention and possible BO. At that point, it is not speculation but buying based on realistic future potential. I agree that the large PPS increase may not occur right away, but once R-It results are publicized, I would anticipate a steady increase to $20 level and potentially beyond.
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