You never know what will happen (or not happen) that might cause those options to expire worthless. For longs who invested years ago, believing in the science, who might now have to watch those options expire worthless due to poor communication from nwbo regarding timelines and strategy, that's a bitter pill to swallow. Especially if (big if) phase 3 finds its way out of the ashes moral victories can't pay the mortgage or the college tuition.
Correction: Owning NWBO stock is like gambling, buying calls like giving money to that Nigerian prince who just needs you to help with some "processing fees" to get his assets unfrozen.
Also saying holders of options are not true longs shows a lack of understanding of how NWBO investing works.
NWBO options are often owned by longs who get sucked in really deeply by the hype surrounding NWBO and want to maximize their potential gain.
It is easy to get suckered in and easy for hype to get started which is why a countervailing force is so badly needed.