As you say perhaps too much Bavi and not enough B2-Gp1 will result in ineffectual one armed Bavi floating around depleting the B2-GP1. I find it still interesting that mch1N11 dosing does not seem to have that problem in the mouse model. The Sloan-Kettering people did not test for B2GP1 levels. I doubt if any of the other mouse tests looked at it either.
Who's managing study protocols?? We're flipping the bill for every study we're doing right now.. Who's driving the bus??
Eleventh Hour Plan.. Getting around the 2 ton elephant.