At this point, I must assume the most conservative stance: that we are approaching 248 events by November 2016 -- not 148. However, if you were correct, I believe the moonshot program would be achieved in 2.5 years -- not 5.
As I understand the situation, there is no chance at all. They did say that there was a safety review triggered if not an efficacy review by the 1st interim. So it is pretty clear that event 148 has long passed.
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