The ones that are done in order to uplist are completely different than doing one to regain or maintain a nasdaq listing. TPIV is most likely doing one now because of all the trial news they plan to provide in the upcoming weeks, months. As long as they provide positive results, then they are far better off on the nasdaq than OTC. If they provide nothing, then you are right, they'll drift back down. But with 4 trials that should all be under way within a few months, this appears to be the start of the TPIV story. All IMHO.