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DewDiligence

08/06/06 4:01 AM

#350 RE: jessellivermore #347

Re: CABG

>Do you know if the company has any interest in re opening the aborted trials involving by-pass surgery?<

Unlikely, IMO. The standard of care in prophylactic anticoagulation for CABG has probably changed since those studies were planned almost a decade ago, and I suspect it would still be a difficult task to define a protocol that surgeons would actually adhere to.

If GTC decides at some point to embark on a new CABG program, it could be directed at overcoming the cognitive deficit associated with CABG, which is a separate indication from GTC’s old CABG program that sought to overcome heparin resistance. But I think this, too, is unlikely.