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Re: jessellivermore post# 347

Sunday, 08/06/2006 4:01:10 AM

Sunday, August 06, 2006 4:01:10 AM

Post# of 19309
Re: CABG

>Do you know if the company has any interest in re opening the aborted trials involving by-pass surgery?<

Unlikely, IMO. The standard of care in prophylactic anticoagulation for CABG has probably changed since those studies were planned almost a decade ago, and I suspect it would still be a difficult task to define a protocol that surgeons would actually adhere to.

If GTC decides at some point to embark on a new CABG program, it could be directed at overcoming the cognitive deficit associated with CABG, which is a separate indication from GTC’s old CABG program that sought to overcome heparin resistance. But I think this, too, is unlikely.

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