Is low as in IMPROVE-IT (69.8 / 53.2 @ 1 yr and more or less reamined flat till the end of the study) or a little bit higher? ... Both case I am fine with the event rate ... I-IT was 5.78 / 5.54 ...same rate (with 4.84% composite) will mean 33% / 26% RRR ... if a little bit higher (e.g. 5.9% ...) -> 36%