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HDGabor

09/09/14 6:03 PM

#33939 RE: zumantu #33938

Power is not effects the timing of the interim analysis. Read this.

At 967 events eff% will determine the power.
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Whalatane

09/09/14 7:14 PM

#33940 RE: zumantu #33938

Zuman

I don't think the FDA will agree to a lower powered trial.
Nor do I think that Amarin should try and shorten the trial at a lower power ...it makes the results less convincing IMHO

Amarin has already sunk a ton of $ and time into this ..the last thing they want is the results dismissed because the trial was considered under powered.
JMO
Kiwi